The team confirmed the finding by recreating the defect in breast cancer cells in the laboratory. Once CDKN1B was switched off, the cells became resistant to hormone drugs. But when the missing p27 protein was restored, the medicines started working again.
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Scientists identify genetic defect that makes breast cancer treatment ineffective
April 28, 2026The team confirmed the finding by recreating the defect in breast cancer cells in the laboratory. Once CDKN1B was switched off, the cells became resistant to hormone drugs. But when the missing p27 protein was restored, the medicines started working again.